Resources

Looking for useful informational resources and materials? You're in the right place.

Whether you're on YUPELRI, considering it, or just want to learn more about COPD, this is your destination for useful informational resources and guidance.

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Frequently Asked Questions

About COPD

  • What is COPD?

    COPD stands for chronic obstructive pulmonary disease. It can also be called chronic bronchitis, emphysema, or both.

    LEARN MORE

  • What symptoms should I look out for?

    Symptoms like coughing, wheezing, and shortness of breath are common.

    LEARN MORE

  • What’s the difference between maintenance and rescue medications? When should I take them?

    Maintenance medications are taken every day and work over time to help control symptoms. Rescue medicines relieve sudden symptoms, but too much of this medication will increase your risk of serious (possibly fatal) side effects. Follow your doctor's instructions for taking your medication.

    LEARN MORE

  • What is a nebulizer?

    A nebulizer gets medicine into your lungs in a fine mist while you breathe calmly, deeply, and evenly through a mouthpiece until the mist is gone. Requires setup and cleaning.

    LEARN MORE

  • What are some important things to know about inhalers?

    Compact and portable. Different inhalers require different breathing techniques to get the medicine into your lungs.

    LEARN MORE

About YUPELRI

  • When should I ask my doctor about YUPELRI?

    You may want to talk to your doctor if you:

    • are experiencing COPD symptoms and are curious about your treatment options
    • are using your inhaler more often than prescribed and you’re wondering if nebulized YUPELRI could be right for you
    • have had a positive experience with a nebulizer and are interested in a once-daily maintenance option

    LEARN MORE

Taking YUPELRI

  • How do I take YUPELRI?

    You take YUPELRI with a standard jet nebulizer with a mouthpiece. You take YUPELRI once a day. Breathe normally using the nebulizer mouthpiece for about 8 minutes or until you don't see any mist in the nebulizer.* Setup and cleaning time are required.

    *Using the PARI LC® SPRINT Nebulizer.

    LEARN MORE

  • What should I know about using a jet nebulizer?

    Once people use a jet nebulizer, some may prefer it. It gets the medicine into your lungs, where you need it most. Setup and cleaning required.

    LEARN MORE

  • How do you clean a nebulizer?

    Many nebulizer parts can be washed with dish soap and warm water. Some pieces can be placed on the top rack of the dishwasher. Be sure to follow the manufacturer’s instructions.

    LEARN MORE

Common Caregiver Questions

  • How can I best help my loved one with COPD?

    There are ways to help. Talk openly and allow family members to be heard. Educate your family on COPD—this can help everyone feel more in control. Track triggers and symptoms to share with your loved one’s healthcare provider.

    LEARN MORE

  • What if caregiving gets overwhelming?

    At some point, the stress of caregiving may make you feel depressed or overwhelmed. Be sure to ask for help with caregiving tasks so you can take time out to care for yourself. And if you need it, ask a doctor how to get support within your community.

    LEARN MORE

Access and Coverage

  • Is YUPELRI covered under Medicare Part B?

    If you’re 65 years of age or older, Medicare Part B may reimburse up to 100% of the cost of your YUPELRI prescription as well as a standard jet nebulizer (no guarantee of coverage). Check with your insurance provider for more information.

    LEARN MORE

  • What is the YUPELRI Savings Card?

    For patients with commercial insurance, the YUPELRI Savings Card can be used to reduce the amount of your out-of-pocket expense up to a maximum of $550 per 30-day prescription. No other purchase is necessary. This offer can be used up to a total of 12 times per calendar year while this program remains in effect, with a maximum savings amount of $6,600 per calendar year. Valid prescription with Prescriber ID# required. Please see full terms and conditions.

Important Safety Information

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What is YUPELRI®?

  • YUPELRI is a prescription medicine used to treat chronic obstructive pulmonary disease (COPD), a long-term (chronic) lung disease that includes chronic bronchitis, emphysema, or both.
  • It is an anticholinergic medicine which helps the muscles around the airway in your lungs stay relaxed to prevent symptoms such as wheezing, cough, chest tightness, and shortness of breath.
  • It is used long-term as 1 vial of YUPELRI, 1 time each day inhaled through your nebulizer to improve symptoms of COPD for better breathing.

What is YUPELRI®?

  • YUPELRI is a prescription medicine used to treat chronic obstructive pulmonary disease (COPD), a long-term (chronic) lung disease that includes chronic bronchitis, emphysema, or both.
  • It is an anticholinergic medicine which helps the muscles around the airway in your lungs stay relaxed to prevent symptoms such as wheezing, cough, chest tightness, and shortness of breath.
  • It is used long-term as 1 vial of YUPELRI, 1 time each day inhaled through your nebulizer to improve symptoms of COPD for better breathing.

Who should not use YUPELRI?

  • Do not use YUPELRI if you have sudden breathing problems. Always have a rescue inhaler with you.
  • Do not use YUPELRI if you have had an allergic reaction to revefenacin, or any of the other ingredients in YUPELRI (sodium chloride, citric acid, sodium citrate).
  • Do not use in children. It is not known if YUPELRI is safe and effective in children.

Before using YUPELRI, tell your healthcare provider about all your medical conditions, including if you:

  • have eye problems such as glaucoma. YUPELRI may make your glaucoma worse.
  • have prostate or bladder problems, or problems passing urine. YUPELRI may make these problems worse.
  • have liver problems.
  • are allergic to any of the ingredients in YUPELRI, or any other medicines.
  • are pregnant or planning to become pregnant. It is not known if YUPELRI may harm your unborn baby.
  • are breastfeeding. It is not known if the medicine in YUPELRI passes into your breast milk and if it can harm your baby.

Tell your healthcare provider about all the medicines you take including prescription and over-the-counter medicines, vitamins, and herbal supplements. YUPELRI and certain other medicines may interact with each other. This may cause serious side effects.

Especially tell your healthcare provider if you take:

  • Other anticholinergics (including tiotropium, ipratropium, aclidinium, umeclidinium, glycopyrrolate)
  • Atropine

Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist each time you get a new medicine.

What are the possible side effects with YUPELRI?

YUPELRI can cause serious side effects, including:

  • Sudden breathing problems immediately after inhaling your medicine. If you have sudden breathing problems immediately after inhaling your medicine, stop using YUPELRI and call your healthcare provider right away.
  • New or worsened eye problems including acute narrow-angle glaucoma. Acute narrow-angle glaucoma can cause permanent loss of vision if not treated. Symptoms may include:
    • Red eyes
    • Blurred vision
    • Seeing halos or bright colors around lights
    • Eye pain or discomfort
    • Nausea or vomiting
  • Urinary retention. People who take YUPELRI may develop new or worse urinary retention. Symptoms of urinary retention may include:
    • difficulty urinating
    • urinating frequently
    • urination in a weak stream or drips
    • painful urination

If you have any of these symptoms, call your healthcare provider right away before taking another dose.

  • Serious allergic reactions. Call your healthcare provider or get emergency medical care if you get any of the following symptoms of a serious allergic reaction:
    • rash
    • hives
    • severe itching
    • swelling of your face, mouth, and tongue
    • difficulty breathing or swallowing

If you have any of these symptoms, stop taking YUPELRI, and call your healthcare provider right away before taking another dose.

Common side effects of YUPELRI include:

  • Cough
  • Runny nose
  • Upper respiratory tract infection
  • Headache
  • Back pain

Tell your healthcare provider if you get any side effects that bother you or that do not go away. These are not all the possible side effects with YUPELRI. Ask your healthcare provider or pharmacist for more information. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

How should I use YUPELRI?

Read the step by step instructions for using YUPELRI at the end of this Patient Information Leaflet

  • YUPELRI is only for use with a nebulizer.
  • Do not use YUPELRI more often than prescribed.
  • Do not mix YUPELRI with other medicines in your nebulizer.
  • Do not use other medicines that contain an anticholinergic for any reason.
  • Do not stop using YUPELRI, even if you are feeling better, unless your healthcare provider tells you to because your symptoms might get worse.
  • Call your healthcare provider or get emergency medical care right away if
    • your breathing problems get worse.
    • you need to use your rescue inhaler medicine more often than usual.
    • your rescue inhaler medicine does not relieve your symptoms.

This summary does not include all the information about YUPELRI and is not meant to take the place of a discussion with your healthcare provider about your treatment.

Please see the full Prescribing Information. For additional information please contact us at 1-800-395-3376.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

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